Publications

Molecular mechanism governing the plasticity of use-dependent spike broadening in dorsal root ganglion neurons.

Alexander TD, Tymanskyj S, Kennedy KJ, Kaczmarek LK, Covarrubias M.Proc Natl Acad Sci U S A. 2025 Jan 7;122(1):e2411033121. doi: 10.1073/pnas.2411033121. Epub 2024 Dec 31.PMID: 39739796 Free PMC article.

Optogenetic control of receptor-mediated growth cone dynamics in neurons.

Tymanskyj SR, Escorce A, Karthikeyan S, Ma L.Mol Biol Cell. 2025 Feb 1;36(2):br5. doi: 10.1091/mbc.E23-07-0268. Epub 2024 Dec 20.PMID: 39705378 Free PMC article.

Tunable Action Potential Repolarization Governed by Kv3.4 Channels in Dorsal Root Ganglion Neurons.

Alexander TD, Muqeem T, Zhi L, Tymanskyj SR, Covarrubias M.J Neurosci. 2022 Nov 16;42(46):8647-8657. doi: 10.1523/JNEUROSCI.1210-22.2022.PMID: 36198500 Free PMC article.

γ-secretase promotes Drosophila postsynaptic development through the cleavage of a Wnt receptor.

Restrepo LJ, DePew AT, Moese ER, Tymanskyj SR, Parisi MJ, Aimino MA, Duhart JC, Fei H, Mosca TJ.Dev Cell. 2022 Jul 11;57(13):1643-1660.e7. doi: 10.1016/j.devcel.2022.05.006. Epub 2022 Jun 1.PMID: 35654038 Free PMC article.5Cite

Selective axonal transport through branch junctions is directed by growth cone signaling and mediated by KIF1/kinesin-3 motors.

Tymanskyj SR, Curran BM, Ma L.Cell Rep. 2022 Apr 26;39(4):110748. doi: 10.1016/j.celrep.2022.110748.PMID: 35476993 Free PMC article.6Cite

PKCε associates with the Kv3.4 channel to promote its expression in a kinase activity-dependent manner.

Zemel BM, Zhi L, Brown EV, Tymanskyj SR, Liang Q, Covarrubias M.FASEB J. 2021 Jan;35(1):e21241. doi: 10.1096/fj.201901877R.PMID: 333686327Cite

MAP7 Prevents Axonal Branch Retraction by Creating a Stable Microtubule Boundary to Rescue Polymerization.

Tymanskyj SR, Ma L.J Neurosci. 2019 Sep 4;39(36):7118-7131. doi: 10.1523/JNEUROSCI.0775-19.2019. Epub 2019 Aug 7.PMID: 31391261 Free PMC article.

MAP7 regulates axon morphogenesis by recruiting kinesin-1 to microtubules and modulating organelle transport.

Tymanskyj SR, Yang BH, Verhey KJ, Ma L.Elife. 2018 Aug 22;7:e36374. doi: 10.7554/eLife.36374.PMID: 30132755 Free PMC article.9Cite

Calcineurin Dysregulation Underlies Spinal Cord Injury-Induced K⁺ Channel Dysfunction in DRG Neurons.

Zemel BM, Muqeem T, Brown EV, Goulão M, Urban MW, Tymanskyj SR, Lepore AC, Covarrubias M.J Neurosci. 2017 Aug 23;37(34):8256-8272. doi: 10.1523/JNEUROSCI.0434-17.2017. Epub 2017 Jul 27.PMID: 28751455 Free PMC article.

A Role for AnkyrinG in Maturation and Maintenance of the Nodes of Ranvier.

Yang B, Curran BM, Tymanskyj SR.J Neurosci. 2017 Jun 14;37(24):5796-5797. doi: 10.1523/JNEUROSCI.0858-17.2017.PMID: 28615476 Free PMC article. No abstract available.

MAP7 Regulates Axon Collateral Branch Development in Dorsal Root Ganglion Neurons.

Tymanskyj SR, Yang B, Falnikar A, Lepore AC, Ma L.J Neurosci. 2017 Feb 8;37(6):1648-1661. doi: 10.1523/JNEUROSCI.3260-16.2017. Epub 2017 Jan 9.PMID: 28069923 Free PMC article.

Dcc Mediates Functional Assembly of Peripheral Auditory Circuits.

Kim YJ, Wang SZ, Tymanskyj S, Ma L, Tao HW, Zhang LI.Sci Rep. 2016 Apr 4;6:23799. doi: 10.1038/srep23799.PMID: 27040640 Free PMC article.

Dendrite self-avoidance requires cell-autonomous slit/robo signaling in cerebellar purkinje cells.

Gibson DA, Tymanskyj S, Yuan RC, Leung HC, Lefebvre JL, Sanes JR, Chédotal A, Ma L.Neuron. 2014 Mar 5;81(5):1040-1056. doi: 10.1016/j.neuron.2014.01.009.PMID: 24607227 Free PMC article.

MAP1B enhances microtubule assembly rates and axon extension rates in developing neurons.

Tymanskyj SR, Scales TM, Gordon-Weeks PR.Mol Cell Neurosci. 2012 Feb;49(2):110-9. doi: 10.1016/j.mcn.2011.10.003. Epub 2011 Oct 17.PMID: 22033417

Evolution of the spatial distribution of MAP1B phosphorylation sites in vertebrate neurons.

Tymanskyj SR, Lin S, Gordon-Weeks PR.J Anat. 2010 Jun;216(6):692-704. doi: 10.1111/j.1469-7580.2010.01228.x. Epub 2010 Apr 9.PMID: 20408908 Free PMC article.